Anticorps Recombinant de lapin anti-TBX4/5

TBX4/5 Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242565F1

N° de cat : 84997-4-PBS

Synonymes

TBX5, HOS, T box 5, T-box protein 5, T-box transcription factor TBX5

---

Galerie de données de validation

• 

  IF Staining of U2OS using 84997-4-RR (same clone as 84997-4-PBS)

  Immunofluorescent analysis of (4% PFA) fixed U2OS cells using TBX5 antibody (84997-4-RR, Clone: 242565F1 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 84997-4-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 84997-4-RR

  Biolayer interferometry (BLl) kinetic assays of 84997-4-RR against Human TBX4/5 were performed. The affinity constant is 37.3 nM.

---

Informations sur le produit

84997-4-PBS cible TBX4/5 dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TBX4/5 Protéine recombinante Ag3845
• Nom complet: T-box 5
• Masse moléculaire calculée: 518 aa, 57 kDa
• Numéro d’acquisition GenBank: BC027942
• Symbole du gène: TBX5
• Identification du gène (NCBI): 6910
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

T-box genes encode a family of transcription factors that have been identified in all metazoans and which play diverse roles during embryonic development. TBX5, a member of T-box family, has an essential role in the initiation of limb outgrowth and heart development. Genetic variation near TBX5 that associates with PR and/or QRS interval variation, which suggests that TBX5 plays a role in CCS function in the general population. Because 77 % amino acid sequence of TBX5 is identical to TBX4, this antibody recognizes both TBX4 and TBX5.

{{ptg:RelatedPrimaryAntibodies}}