Anticorps Monoclonal anti-TCEB1

TCEB1 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2D6D8

N° de cat : 68164-1-PBS

Synonymes

2D6D8, EloC, Elongin 15 kDa subunit, Elongin C, Elongin-C

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Galerie de données de validation

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  WB analysis using 68164-1-Ig (same clone as 68164-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68164-1-Ig (TCEB1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68164-1-PBS in a different storage buffer formulation.

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  IF Staining of T-47D using 68164-1-Ig (same clone as 68164-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed T-47D cells using TCEB1 antibody (68164-1-Ig, Clone: 2D6D8 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68164-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68164-1-PBS cible TCEB1 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: TCEB1 Protéine recombinante Ag22601
• Nom complet: transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
• Masse moléculaire calculée: 112 aa, 12 kDa
• Poids moléculaire observé: 12 kDa
• Numéro d’acquisition GenBank: BC013809
• Symbole du gène: TCEB1
• Identification du gène (NCBI): 6921
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TCEB1, also named as RNA polymerase II transcription factor SIII subunit C, belongs to the SKP1 family. It mediates the ubiquitination of ECS-E3 ubiquitin-protein ligase complexes. TCEB1 is overexpressed in prostate cancer cell line PC-3 and breast cancer cell line SK-BR-3. TCEB1 also promotes invasion of prostate cancer cells (PMID:18844214).

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