Anticorps Recombinant de lapin anti-TCR Vγ5Vδ1

TCR Vγ5Vδ1 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

251677A1

N° de cat : 98527-1-RR

Synonymes

TCR gamma delta, Vγ5Vδ1

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Galerie de données de validation

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  FC experiment of human PBMCs using 98527-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-TCR Vγ5Vδ1 Rabbit RecAb (98527-1-RR, Clone:251677A1) , or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD3. Cells were not fixed. Lymphocytes were gated.

• 

  FC experiment of human PBMCs using 98527-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-TCR Vγ5Vδ1 Rabbit RecAb (98527-1-RR, Clone:251677A1)(red) , or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9)(blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98527-1-RR cible TCR Vγ5Vδ1 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: TCR Vγ5Vδ1
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

TCR Vγ5Vδ1 refers to a specific type of T cell receptor (TCR) found on γδ T cells. These cells are a distinct subset of T lymphocytes that play a role in immune responses, particularly in maintaining tissue integrity and responding to stress signals. The Vγ5Vδ1 TCR is uniquely expressed on a population of T cells called dendritic epidermal T cells (DETCs) that reside in the epidermis (PMID: 35260830, 35031803). The Vγ5Vδ1 TCR-CD3 complex forms an asymmetric dimer, with the Vγ5 domains of each protomer interacting to create a back-to-back structure. This dimeric form is essential for T cell activation (PMID: 38657677).

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