Anticorps Recombinant de lapin anti-TCR Vγ9Vδ2

TCR Vγ9Vδ2 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

251678A1

N° de cat : 98526-1-PBS

Synonymes

TCR gamma delta, Vγ9Vδ2

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Galerie de données de validation

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  FC experiment of human PBMCs using 98526-1-RR (same clone as 98526-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-TCR Vγ9Vδ2 Rabbit RecAb (98526-1-RR, Clone:251678A1), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD3. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98526-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98526-1-RR (same clone as 98526-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-TCR Vγ9Vδ2 Rabbit RecAb (98526-1-RR, Clone:251678A1)(red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9)(blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98526-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98526-1-PBS cible TCR Vγ9Vδ2 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: TCR Vγ9Vδ2
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

TCR Vγ9Vδ2 refers to a specific type of T cell receptor (TCR) found on a subset of gamma delta (γδ) T cells called Vγ9Vδ2 T cells. These cells are a major population of human γδ T cells in the blood and are characterized by the expression of a unique TCR that recognizes phosphoantigens (pAg). Vγ9Vδ2 T cell activation is tightly regulated by a variety of activating or inhibitory receptors which are specific for constitutively expressed or stress-modulated ligands (PMID: 20447835, 40040716). The most effective TCR Vg9Vd2-mediated cell activation relies on TCR interaction with BTN3A1, BTN3A2, and BTN2A1 molecules expressed by target cells (PMID: 25566259).

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