Anticorps Recombinant de lapin anti-TCR beta

TCR beta Recombinant Antibody for FC

Hôte / Isotype

Hamster / IgG2a

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

H57-597

N° de cat : 65678-1-AR

Synonymes

Tcrb, T cell receptor beta chain, TCRβ, Tib

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 65678-1-AR

  1x10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse TCR beta Hamster IgG2a RecAb (65678-1-AR, Clone: H57-597) or Armenian Hamster IgG Isotype Control (PIP) (65210-1-Ig, Clone: PIP), and FITC-conjugated Anti-Armenian Hamster IgG antibody. Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD3. Cells were not fixed.

• 

  FC experiment of mouse splenocytes using 65678-1-AR

  1x10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse TCR beta Hamster IgG2a RecAb (65678-1-AR, Clone: H57-597) (red) or Armenian Hamster IgG Isotype Control (PIP) (65210-1-Ig, Clone: PIP) (blue), and FITC-conjugated Anti-Armenian Hamster IgG antibody. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

65678-1-AR cible TCR beta dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Hamster / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: s/o
• Nom complet: T-cell receptor beta chain
• Symbole du gène: TCR beta
• Identification du gène (NCBI): 21577
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Stable for one year after shipment.

Informations générales

T-cell receptor (TCR) consists of heterodimeric glycoproteins (TCR alpha/beta or gamma/delta) that demonstrate homology with immunoglobulins (PMID: 2144901). TCR beta is a member of the immunoglobulin superfamily and is expressed on alpha/beta TCR-bearing T cells and thymocytes. The TCR heterodimers are noncovalently associated with CD3. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta (PMID: 1826255). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).

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