Anticorps Recombinant de lapin anti-TCR beta

TCR beta Recombinant Antibody for FC

Hôte / Isotype

Hamster / IgG2a

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

H57-597

N° de cat : 65678-1-PBS

Synonymes

Tcrb, T cell receptor beta chain, TCRβ, Tib

---

Galerie de données de validation

• 

  FC experiment of mouse splenocytes using 65678-1-AR (same clone as 65678-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse TCR beta Hamster IgG2a RecAb (65678-1-AR, Clone: H57-597) or Armenian Hamster IgG Isotype Control (PIP) (65210-1-Ig, Clone: PIP), and FITC-conjugated Anti-Armenian Hamster IgG antibody. Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD3. Cells were not fixed. This data was developed using the same antibody clone with 65678-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse splenocytes using 65678-1-AR (same clone as 65678-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse TCR beta Hamster IgG2a RecAb (65678-1-AR, Clone: H57-597) (red) or Armenian Hamster IgG Isotype Control (PIP) (65210-1-Ig, Clone: PIP) (blue), and FITC-conjugated Anti-Armenian Hamster IgG antibody. Cells were not fixed. This data was developed using the same antibody clone with 65678-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

65678-1-PBS cible TCR beta dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Hamster / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: s/o
• Nom complet: T-cell receptor beta chain
• Symbole du gène: TCR beta
• Identification du gène (NCBI): 21577
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

T-cell receptor (TCR) consists of heterodimeric glycoproteins (TCR alpha/beta or gamma/delta) that demonstrate homology with immunoglobulins (PMID: 2144901). TCR beta is a member of the immunoglobulin superfamily and is expressed on alpha/beta TCR-bearing T cells and thymocytes. The TCR heterodimers are noncovalently associated with CD3. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta (PMID: 1826255). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).

{{ptg:RelatedPrimaryAntibodies}}