Anticorps Polyclonal de lapin anti-TEAD2

• Phare
• Validé par KD/KO

TEAD2 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris et plus (1)

Applications

WB, ChIP, ELISA

Conjugaison

Non conjugué

Publications

9

N° de cat : 21159-1-AP

Synonymes

ETF, TEA domain family member 2, TEAD 2, TEAD2, TEF 4, TEF4

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Galerie de données de validation

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  WB analysis of mouse colon using 21159-1-AP

  mouse colon tissue were subjected to SDS PAGE followed by western blot with 21159-1-AP (TEAD2 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse lung using 21159-1-AP

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 21159-1-AP (TEAD2 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu de côlon de souris, tissu pulmonaire de souris

Dilution recommandée

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 2 publications below
• WB: See 8 publications below
• ChIP: See 1 publications below

Informations sur le produit

21159-1-AP cible TEAD2 dans les applications de WB, ChIP, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TEAD2 Protéine recombinante Ag14074
• Nom complet: TEA domain family member 2
• Masse moléculaire calculée: 447 aa, 49 kDa
• Poids moléculaire observé: 55-65 kDa
• Numéro d’acquisition GenBank: BC051301
• Symbole du gène: TEAD2
• Identification du gène (NCBI): 8463
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

TEAD2 belongs to a protein family that share the TEA/ATTS domain. It acts as a transcriptional factor by cooperatively binding to the GT-IIC and Sph(I 1 II) enhansons in the simian virus 40 (SV40) enhancer. Also it can modulate SV40 late transcription together with large T antigen. The transcriptional activity of TEAD2 required several regions of the proteins , a TBP-associated factors and a limiting transcriptional intermediary factors. TEAD2 also preforms an essential role in the Hippo signaling pathway. TEAD2 regulates gene expression of YAP1 and WWTR1/TAZ, thus mediating cell proliferation, migration and epithelial mesenchymal transition induction. TEAD2 is strongly expressed in human ovarian carcinoma cell line.

Publications

Species	Application	Title
human,rat	WB	ACS Nano; Hepatic Stellate Cell- and Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis; Authors - Xia Niu
mouse	WB	J Cell Biol; Thyroid hormone regulates muscle fiber type conversion via miR-133a1.; Authors - Duo Zhang
human	WB	Aging (Albany NY); Integrative bioinformatics and experimental analysis revealed TEAD as novel prognostic target for hepatocellular carcinoma and its roles in ferroptosis regulation.; Authors - Xinxin Ren ; KD Validated
human	WB	Oncol Rep; 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells.; Authors - Yu Zuo
human	WB	Int J Gen Med; Significance of TEAD Family in Diagnosis, Prognosis and Immune Response for Ovarian Serous Carcinoma.; Authors - Xinxin Ren ; KD Validated
mouse	WB	Cell Rep; YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways.; Authors - Jiadong Liu