Anticorps Monoclonal anti-TELO2

TELO2 Monoclonal Antibody for WB, IHC, IF/ICC, IP, Cytometric bead array, Sandwich ELISA, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat

Applications

WB, IHC, IF/ICC, IP, Cytometric bead array, Sandwich ELISA, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3H10F4

N° de cat : 66077-1-PBS

Synonymes

TEL2, Protein clk-2 homolog, Protein clk 2 homolog, KIAA0683, hCLK2

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Galerie de données de validation

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  WB analysis using 66077-1-Ig (same clone as 66077-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66077-1-Ig (TELO2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66077-1-PBS in a different storage buffer formulation.

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  WB analysis of Y79 using 66077-1-Ig (same clone as 66077-1-PBS)

  Y79 cells were subjected to SDS PAGE followed by western blot with 66077-1-Ig (TELO2 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66077-1-PBS in a different storage buffer formulation.

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  WB analysis of L02 using 66077-1-Ig (same clone as 66077-1-PBS)

  L02 cells were subjected to SDS PAGE followed by western blot with 66077-1-Ig (TELO2 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66077-1-PBS in a different storage buffer formulation.

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  WB analysis of A431 using 66077-1-Ig (same clone as 66077-1-PBS)

  A431 cells were subjected to SDS PAGE followed by western blot with 66077-1-Ig (TELO2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66077-1-PBS in a different storage buffer formulation.

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  Sandwich ELISA standard curve of MP50016-1

  Sandwich ELISA standard curve of MP50016-1, TELO2 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 66077-2-PBS. Detection antibody: HRP-conjugated 66077-1-PBS. Standard: Ag8834. Range: 0.156-20 ng/mL.

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  IP experiment of HepG2 using 66077-1-Ig (same clone as 66077-1-PBS)

  IP result of anti-TELO2 (IP:66077-1-Ig, 4ug; Detection:66077-1-Ig 1:500) with HepG2 cells lysate 2900ug. This data was developed using the same antibody clone with 66077-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 66077-1-Ig (same clone as 66077-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66077-1-Ig (TELO2 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66077-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 66077-1-Ig (same clone as 66077-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66077-1-Ig (TELO2 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66077-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 66077-1-Ig (same clone as 66077-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer using 66077-1-Ig(TELO2 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66077-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 66077-1-Ig (same clone as 66077-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer using 66077-1-Ig(TELO2 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66077-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 66077-1-Ig (same clone as 66077-1-PBS)

  Immunofluorescent analysis of () fixed HepG2 cells using 66077-1-Ig (TELO2 antibody) at dilution of 1:25. This data was developed using the same antibody clone with 66077-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP50016-1

  Cytometric bead array standard curve of MP50016-1, TELO2 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 66077-2-PBS. Detection antibody: 66077-1-PBS. Standard: Ag8834. Range: 1.563-12.5 ng/mL.

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Informations sur le produit

66077-1-PBS cible TELO2 dans les applications de WB, IHC, IF/ICC, IP, Cytometric bead array, Sandwich ELISA, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: TELO2 Protéine recombinante Ag8834
• Nom complet: TEL2, telomere maintenance 2, homolog (S. cerevisiae)
• Masse moléculaire calculée: 837 aa, 92 kDa
• Poids moléculaire observé: 92 kDa
• Numéro d’acquisition GenBank: BC017188
• Symbole du gène: TELO2
• Identification du gène (NCBI): 9894
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TELO2 gene encodes a telomere length regulation protein TEL2 homolog. TELO2 may be involved in telomere length regulation and can form TTT complex with TTI1 and TTI2. TTT complex is required to stabilize protein levels of PIKK family proteins and is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), and ultraviolet (UV). The activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals, can be promoted, stabilized and maintained by TELO2.

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