Anticorps Monoclonal anti-TERF1

TERF1 Monoclonal Antibody for Indirect ELISA, WB

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

Indirect ELISA, WB

Conjugaison

Non conjugué

CloneNo.

1D10G4

N° de cat : 67592-1-PBS

Synonymes

Telomeric repeat-binding factor 1, t TRF1, PIN2, NIMA-interacting protein 2, hTRF1 AS

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Galerie de données de validation

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  WB analysis of K-562 using 67592-1-Ig (same clone as 67592-1-PBS)

  K-562 cells were subjected to SDS PAGE followed by western blot with 67592-1-Ig (TERF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67592-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 67592-1-Ig (same clone as 67592-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 67592-1-Ig (TERF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67592-1-PBS in a different storage buffer formulation.

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  WB analysis of Jurkat using 67592-1-Ig (same clone as 67592-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 67592-1-Ig (TERF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67592-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67592-1-PBS cible TERF1 dans les applications de Indirect ELISA, WB et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: TERF1 Protéine recombinante Ag12540
• Nom complet: telomeric repeat binding factor (NIMA-interacting) 1
• Masse moléculaire calculée: 439 aa, 50 kDa
• Poids moléculaire observé: 48-50 kDa
• Numéro d’acquisition GenBank: BC029378
• Symbole du gène: TERF1
• Identification du gène (NCBI): 7013
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Telomeres are nucleoprotein complexes located at chromosome ends that consist of tandem arrays of TTAGGG repeats bound to specific proteins. Telomeres protect chromosome ends from degradation and end-to-end fusions, prevent activation of DNA damage checkpoints, and modulate the maintenance of telomeric DNA by telomerase. TERF1 (telomeric repeat-binding factor 1) binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. It's one component of the shelterin complex, which involved in the regulation of telomere length and protection.

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