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Anticorps Polyclonal de lapin anti-TET3

TET3 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22612-1-PBS

Synonymes

Galerie de données de validation

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  • Immunohistochemistry (IHC) staining of mouse brain tissue using TET3 Polyclonal antibody (22612-1-AP)

    IHC staining of mouse brain using 22612-1-AP (same clone as 22612-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 22612-1-AP (TET3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22612-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using TET3 Polyclonal antibody (22612-1-AP)

    IF Staining of U2OS using 22612-1-AP (same clone as 22612-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using TET3 antibody (22612-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 22612-1-PBS in a different storage buffer formulation.

Informations sur le produit

22612-1-PBS cible TET3 dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène TET3 Protéine recombinante Ag18379
Nom complet tet oncogene family member 3
Masse moléculaire calculée 1660 aa, 179 kDa
Numéro d’acquisition GenBankBC022243
Symbole du gène TET3
Identification du gène (NCBI) 200424
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purifié par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Ten-eleven translocation protein 3 (TET3) belongs to the family of ten-eleven translocations (TETs) which induce DNA demethylation and gene regulation at the epigenetic level by converting 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) (PMID: 31656201). In ovarian cancer, TET3 is reported as an oncogene or tumor suppressor during tumorigenesis and overexpressed in ovarian cancer tissues (PMID: 27141829).

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