Anticorps Polyclonal de lapin anti-TFEC

TFEC Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29324-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 29324-1-AP (same clone as 29324-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29324-1-AP (TFEC antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29324-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 29324-1-AP (same clone as 29324-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29324-1-AP (TFEC antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29324-1-PBS in a different storage buffer formulation.

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Informations sur le produit

29324-1-PBS cible TFEC dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TFEC Protéine recombinante Ag30973
• Nom complet: transcription factor EC
• Masse moléculaire calculée: 347 aa, 39 kDa
• Poids moléculaire observé: 37-50 kDa
• Numéro d’acquisition GenBank: BC029891
• Symbole du gène: TFEC
• Identification du gène (NCBI): 22797
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The DNA-binding factor TFE3 contains adjacent helix-loop-helix (HLH) and leucine zipper (LZ) domains flanked by an upstream basic region. These protein motifs are frequently observed in other transcription factors and are particularly common to members of the Myc family. TFEC shares a bHLH/LZ structure with TFE3 and a closely related protein microphthalmia-associated transcription factor (MITF), which is critically involved in melanocyte differentiation. The expression of TFEC is mainly in fibroblasts, myoblasts, chondrosarcoma cells and myeloma cells. 50kDa human TFEC isoforms are produced by alternative splicing (PMID: 29303964, PMID: 11467950).

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