Anticorps Recombinant de lapin anti-TICAM2

TICAM2 Recombinant Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241186C12

N° de cat : 84064-6-PBS

Synonymes

241186C12, MyD88-4, Putative NF-kappa-B-activating protein 502, TICAM 2, TICAM-2

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Galerie de données de validation

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  IHC staining of mouse testis using 84064-6-RR (same clone as 84064-6-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 84064-6-RR (TICAM2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84064-6-PBS in a different storage buffer formulation.

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  IF Staining of PC-3 using 84064-6-RR (same clone as 84064-6-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed PC-3 cells using TICAM2 antibody (84064-6-RR, Clone: 241186C12 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84064-6-PBS in a different storage buffer formulation.

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Informations sur le produit

84064-6-PBS cible TICAM2 dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: toll-like receptor adaptor molecule 2
• Masse moléculaire calculée: 27 kDa
• Numéro d’acquisition GenBank: NM_021649
• Symbole du gène: TICAM2
• Identification du gène (NCBI): 353376
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TICAM2, also named TIRAP3, TIRP, and TRAM, is involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1. TICAM2 is involved in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS.

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