Anticorps Recombinant de lapin anti-TIMP2

TIMP2 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

243160E10

N° de cat : 83938-3-PBS

Synonymes

TIMP-2, CSC 21K, CSC-21K, Metalloproteinase inhibitor 2, TIMP 2

---

Galerie de données de validation

• 

  WB analysis using 83938-3-RR (same clone as 83938-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83938-3-RR (TIMP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83938-3-PBS in a different storage buffer formulation.

---

Informations sur le produit

83938-3-PBS cible TIMP2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TIMP2 Protéine recombinante Eg0430
• Nom complet: TIMP metallopeptidase inhibitor 2
• Masse moléculaire calculée: 220 aa, 24 kDa
• Poids moléculaire observé: 21-24 kDa
• Numéro d’acquisition GenBank: BC052605
• Symbole du gène: TIMP2
• Identification du gène (NCBI): 7077
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The TIMPs are natural highly specific endogenous inhibitors of MMPs. Human TIMP family consists of four 21-28 kDa proteins known as TIMP1, TIMP2, TIMP3, and TIMP4 encoded by four paralogous genes.TIMPs are vital to the maintenance of ECM homeostasis primarily through their MMP inhibitory functions. TIMP2, a member of the TIMP family, regulates the proteolytic activity of all MMPs and is involved in cell differentiation, growth, migration, angiogenesis, and apoptosis. Urinary TIMP2 has been recently recognized as an early biomarker to predict Acute kidney injury (AKI) in critically ill patients.

{{ptg:RelatedPrimaryAntibodies}}