Anticorps Recombinant de lapin anti-TIMP2

TIMP2 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

250231B8

N° de cat : 85882-2-RR

Synonymes

Metalloproteinase inhibitor 2, Timp-2, Tissue inhibitor of metalloproteinases 2

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Galerie de données de validation

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  WB analysis of A172 using 85882-2-RR

  A172 cells were subjected to SDS PAGE followed by western blot with 85882-2-RR (Timp2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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  WB analysis using 85882-2-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 85882-2-RR (Timp2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: A172 cells, tissu testiculaire de rat, tissu testiculaire de souris

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

85882-2-RR cible TIMP2 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TIMP2 Protéine recombinante Eg2960
• Nom complet: tissue inhibitor of metalloproteinase 2
• Masse moléculaire calculée: 24 kDa
• Poids moléculaire observé: 20-24 kDa
• Numéro d’acquisition GenBank: uniprot无NM号
• Symbole du gène: Timp2
• Identification du gène (NCBI): 21858
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

The TIMPs are natural highly specific endogenous inhibitors of MMPs. Human TIMP family consists of four 21-28 kDa proteins known as TIMP1, TIMP2, TIMP3, and TIMP4 encoded by four paralogous genes.TIMPs are vital to the maintenance of ECM homeostasis primarily through their MMP inhibitory functions. TIMP2, a member of the TIMP family, regulates the proteolytic activity of all MMPs and is involved in cell differentiation, growth, migration, angiogenesis, and apoptosis. Urinary TIMP2 has been recently recognized as an early biomarker to predict Acute kidney injury (AKI) in critically ill patients.

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