Anticorps Polyclonal de lapin anti-TINP1

TINP1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16230-1-PBS

Synonymes

HUSSY-29, HUSSY29, HCL G1, Hairy cell leukemia protein 1, Hairy cell leukemia

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Galerie de données de validation

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  WB analysis using 16230-1-AP (same clone as 16230-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16230-1-AP (TINP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16230-1-PBS in a different storage buffer formulation.

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  WB analysis of Caco-2 using 16230-1-AP (same clone as 16230-1-PBS)

  Caco-2 cells were subjected to SDS PAGE followed by western blot with 16230-1-AP (TINP1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16230-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 16230-1-AP (same clone as 16230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 16230-1-AP (TINP1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16230-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 16230-1-AP (same clone as 16230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 16230-1-AP (TINP1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16230-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 16230-1-AP (same clone as 16230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 16230-1-AP (TINP1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16230-1-PBS in a different storage buffer formulation.

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Informations sur le produit

16230-1-PBS cible TINP1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TINP1 Protéine recombinante Ag8822
• Nom complet: TGF beta-inducible nuclear protein 1
• Masse moléculaire calculée: 260 aa, 30 kDa
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: BC005288
• Symbole du gène: TINP1
• Identification du gène (NCBI): 10412
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TINP1 (TGF beta inducible nuclear protein 1) was widely expressed in various cell lines. TINP1 overexpression significantly promoted tumor cell proliferation, which may be associated with the downregulation of p53 expression. Furthermore, TINP1 promoted a number of cell lines to the S phase of the cell cycle. TINP1 promotes cell proliferation and significantly reduces p53 and p21 expression.

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