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Anticorps Polyclonal de lapin anti-TIPIN

TIPIN Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11972-2-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using TIPIN Polyclonal antibody (11972-2-AP)

    WB analysis using 11972-2-AP (same clone as 11972-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11972-2-AP (TIPIN antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11972-2-PBS in a different storage buffer formulation.

Informations sur le produit

11972-2-PBS cible TIPIN dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène TIPIN Protéine recombinante Ag2595
Nom complet TIMELESS interacting protein
Masse moléculaire calculée 301 aa, 34 kDa
Poids moléculaire observé 48 kDa
Numéro d’acquisition GenBankBC000870
Symbole du gène TIPIN
Identification du gène (NCBI) 54962
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TIPIN, also named as TIMELESS-interacting protein, is a 301 amino acid protein, which belongs to the CSM3 family. TIPIN Plays an important role in the control of DNA replication and the maintenance of replication fork stability. TIPIN forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress. The calculated molecular weight of TIPIN is 34 kDa, but the result of WB is 55-60 kDa, which is similar to the result of publication.(PMID: 24830473)

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