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Anticorps Polyclonal de lapin anti-TLE4

TLE4 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30959-1-PBS

Synonymes

GRG4, KIAA1261

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using TLE4 Polyclonal antibody (30959-1-AP)

    WB analysis using 30959-1-AP (same clone as 30959-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30959-1-AP (TLE4 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30959-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of K-562 cells using TLE4 Polyclonal antibody (30959-1-AP)

    IP experiment of K-562 using 30959-1-AP (same clone as 30959-1-PBS)

    IP result of anti-TLE4 (IP:30959-1-AP, 4ug; Detection:30959-1-AP 1:800) with K-562 cells lysate 1720 ug. This data was developed using the same antibody clone with 30959-1-PBS in a different storage buffer formulation.

Informations sur le produit

30959-1-PBS cible TLE4 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène TLE4 Protéine recombinante Ag34006
Nom complet transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
Masse moléculaire calculée 84 kDa
Poids moléculaire observé76-88 kDa
Numéro d’acquisition GenBankBC059405
Symbole du gène TLE4
Identification du gène (NCBI) 7091
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TLE4 (Transducin-like enhancer protein 4), also known as GRG4. It is predicted to be located in the nucleus. Tle4 promotes acquisition of corticothalamic identity and blocks emergence of core characteristics of subcerebral/corticospinal projection neuron identity, including gene expression and connectivity. During the first post-natal week, when corticothalamic innervation is ongoing, Tle4 is required to stabilize corticothalamic neuron identity, limiting interference from differentiation programs of developmentally related neuron classes (PMID: 37561632). The molecular weight of TLE4 is 76 kDa.

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