Anticorps Recombinant de lapin anti-TLR4/CD284

TLR4/CD284 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242067C1

N° de cat : 98327-1-PBS

Synonymes

TLR4, 242067C1, ARMD10, CD284, hToll

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Galerie de données de validation

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  FC experiment of human PBMCs using 98327-1-RR (same clone as 98327-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human TLR4/CD284 Rabbit RecAb (98327-1-RR, Clone:242067C1) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Donkey Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD14 Rabbit Recombinant Antibody (CL647-98040, Clone: 230332D7). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98327-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98327-1-RR (same clone as 98327-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human TLR4/CD284 Rabbit RecAb (98327-1-RR, Clone: 242067C1) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Donkey Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98327-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98327-1-PBS cible TLR4/CD284 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: toll-like receptor 4
• Masse moléculaire calculée: 96 kDa
• Numéro d’acquisition GenBank: NM_138554
• Symbole du gène: TLR4
• Identification du gène (NCBI): 7099
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

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