Anticorps Polyclonal de lapin anti-TLR6

• Phare
• Validé par KD/KO

TLR6 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22240-1-PBS

Synonymes

CD286, toll like receptor 6, Toll-like receptor 6

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Galerie de données de validation

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  WB analysis of RAW 264.7 using 22240-1-AP (same clone as 22240-1-PBS)

  RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 22240-1-AP (TLR6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22240-1-PBS in a different storage buffer formulation.

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  WB analysis using 22240-1-AP (same clone as 22240-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 22240-1-AP (TLR6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22240-1-PBS in a different storage buffer formulation.

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  WB analysis of human brain using 22240-1-AP (same clone as 22240-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 22240-1-AP (TLR6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22240-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse thymus using 22240-1-AP (same clone as 22240-1-PBS)

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 22240-1-AP (TLR6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22240-1-PBS in a different storage buffer formulation.

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  WB analysis of Jurkat using 22240-1-AP (same clone as 22240-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 22240-1-AP (TLR6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22240-1-PBS in a different storage buffer formulation.

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  WB analysis of HT-1080 using 22240-1-AP (same clone as 22240-1-PBS)

  HT-1080 cells were subjected to SDS PAGE followed by western blot with 22240-1-AP (TLR6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22240-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22240-1-PBS cible TLR6 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TLR6 Protéine recombinante Ag17686
• Nom complet: toll-like receptor 6
• Masse moléculaire calculée: 480 aa, 56 kDa
• Poids moléculaire observé: 95-110 kDa
• Numéro d’acquisition GenBank: BC111755
• Symbole du gène: TLR6
• Identification du gène (NCBI): 10333
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TLR6, also known as CD286, belongs to the Toll-like receptor (TLR) family, which is important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLR6 can form a heterodimer with TLR2. TLR6 and TLR2 are recruited to the macrophage phagosome, where they recognize peptidoglycan, a Gram-positive pathogen component (PMID: 11095740). TLR6 interacts with CD36, following CD36 stimulation by oxLDL or amyloid-beta 42, and forms a heterodimer with TLR4. The trimeric complex is internalized and triggers an inflammatory response.

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