Anticorps Polyclonal de lapin anti-TMCO3

TMCO3 Polyclonal Antibody for IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31488-1-PBS

Synonymes

C13orf11, FLJ20623, Putative LAG1-interacting protein, Transmembrane and coiled-coil domain-containing protein 3, UNQ2419/PRO4976

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Galerie de données de validation

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  IP experiment of HuH-7 using 31488-1-AP (same clone as 31488-1-PBS)

  IP result of anti-TMCO3 (IP:31488-1-AP, 4ug; Detection:31488-1-AP 1:1000) with HuH-7 cells lysate 880 ug. This data was developed using the same antibody clone with 31488-1-PBS in a different storage buffer formulation.

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  IP experiment of HepG2 using 31488-1-AP (same clone as 31488-1-PBS)

  IP result of anti-TMCO3 (IP:31488-1-AP, 4ug; Detection:31488-1-AP 1:1000) with HepG2 cells lysate 1800 ug. This data was developed using the same antibody clone with 31488-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31488-1-PBS cible TMCO3 dans les applications de IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TMCO3 Protéine recombinante Ag35012
• Nom complet: transmembrane and coiled-coil domains 3
• Masse moléculaire calculée: 75 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC068515
• Symbole du gène: TMCO3
• Identification du gène (NCBI): 55002
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TMCO3, also known as transmembrane and coiled-coil domains 3 or C13orf11, is a protein-coding gene with functional annotation of probable Na+/H+ antiporter. It belongs to the monovalent cation:proton antiporter-2 (CPA2) family according to the Transporter Classification Database (TCDB) (PMID: 33170213). Most CPA2 family members have similar functions and are involved in ion transport (K+, Na+, and H+) in bacteria, archaea, insects, and plants. Upregulated TMCO3 could act as an oncogenic mediator and promote sorafenib resistance in HCC, providing a potential therapeutic target for HCC treatment (PMID: 36304514).

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