Anticorps Polyclonal de lapin anti-TMEM164

TMEM164 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31625-1-PBS

Synonymes

bB360B22.3, transmembrane protein 164

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Galerie de données de validation

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  IHC staining of mouse skeletal muscle using 31625-1-AP (same clone as 31625-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 31625-1-AP (TMEM164 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31625-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse skeletal muscle using 31625-1-AP (same clone as 31625-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 31625-1-AP (TMEM164 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31625-1-PBS in a different storage buffer formulation.

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  IF Staining of U2OS using 31625-1-AP (same clone as 31625-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed U2OS cells using TMEM164 antibody (31625-1-AP) at dilution of 1:400 and CoraLite®594-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-4). This data was developed using the same antibody clone with 31625-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31625-1-PBS cible TMEM164 dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TMEM164 Protéine recombinante Ag34317
• Nom complet: transmembrane protein 164
• Numéro d’acquisition GenBank: BC085605
• Symbole du gène: TMEM164
• Identification du gène (NCBI): 84187
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TMEM164 (Transmembrane Protein 164) is a membrane protein with significant roles in various biological processes, including lipid metabolism, neuroprotection, and cancer regulation. In non-small cell lung cancer (NSCLC), TMEM164 promotes ferroptosis by mediating autophagy, leading to the degradation of ferritin, GPX4, and lipid droplets, which facilitates iron accumulation and lipid peroxidation (PMID: 39798196). In neurodegenerative diseases, TMEM164 overexpression via gene therapy shows promise in reducing neurotoxic reactive astrocyte activation and alleviating disease symptoms (PMID: 37679556).

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