Anticorps Polyclonal de lapin anti-TMEM176B

TMEM176B Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 19825-1-PBS

Synonymes

LR8, Protein LR8, Transmembrane protein 176B

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Galerie de données de validation

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  WB analysis of A549 using 19825-1-AP (same clone as 19825-1-PBS)

  A549 cells were subjected to SDS PAGE followed by western blot with 19825-1-AP (TMEM176B Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19825-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human placenta using 19825-1-AP (same clone as 19825-1-PBS)

  human placenta tissue were subjected to SDS PAGE followed by western blot with 19825-1-AP (TMEM176B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19825-1-PBS in a different storage buffer formulation.

• 

  WB analysis of A549 using 19825-1-AP (same clone as 19825-1-PBS)

  A549 cells were subjected to SDS PAGE followed by western blot with 19825-1-AP (TMEM176B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19825-1-PBS in a different storage buffer formulation.

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Informations sur le produit

19825-1-PBS cible TMEM176B dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TMEM176B Protéine recombinante Ag13918
• Nom complet: transmembrane protein 176B
• Masse moléculaire calculée: 270 aa, 29 kDa
• Poids moléculaire observé: 31 kDa, 23 kDa
• Numéro d’acquisition GenBank: BC004358
• Symbole du gène: TMEM176B
• Identification du gène (NCBI): 28959
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TMEM176B (also known as LR8) is a transmembrane protein belongs to the MS4A family of proteins. It may play a role in the process of maturation of dendritic cells. TMEM176B was first discovered in human lung fibroblasts and is associated with human small cell lung carcinoma. Studies suggest that TMEM176B might be involved in cancer and might serve as targets for antiangiogenic therapy of cancer patients (PMID: 24602018, 22244448). There are two isoforms produced by alternative splicing.

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