Anticorps Polyclonal de lapin anti-TMEM184B

TMEM184B Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28031-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of mouse brain using 28031-1-AP (same clone as 28031-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28031-1-AP (TMEM184B antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28031-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 28031-1-AP (same clone as 28031-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28031-1-AP (TMEM184B antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28031-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse cerebellum using 28031-1-AP (same clone as 28031-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 28031-1-AP (TMEM184B antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28031-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse cerebellum using 28031-1-AP (same clone as 28031-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 28031-1-AP (TMEM184B antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28031-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28031-1-PBS cible TMEM184B dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TMEM184B Protéine recombinante Ag27704
• Nom complet: transmembrane protein 184B
• Numéro d’acquisition GenBank: BC015489
• Symbole du gène: TMEM184B
• Identification du gène (NCBI): 25829
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Transmembrane protein 184B (TMEM184B) is a seven-pass transmembrane protein highly expressed in the nervous system and is thought to play a role in neuronal excitability, synaptic structure, and expression of key developmental and adult pathways involved in neuronal differentiation (PMID: 27122027; 37730546). TMEM184B may activate the MAP kinase signaling pathway (PMID: 12761501). TMEM184B has also been reported to be necessary for interleukin-31-induced itch, promoting adult somatosensation through developmental Wnt signaling and promotion of proper pruriceptive gene expression (PMID: 34629389).

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