Anticorps Polyclonal de lapin anti-TMEM25

• Phare
• Validé par KD/KO

TMEM25 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24361-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 24361-1-AP (same clone as 24361-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24361-1-AP (TMEM25 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24361-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 24361-1-AP (same clone as 24361-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 24361-1-AP (TMEM25 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24361-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24361-1-PBS cible TMEM25 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TMEM25 Protéine recombinante Ag19964
• Nom complet: transmembrane protein 25
• Masse moléculaire calculée: 366 aa, 39 kDa
• Poids moléculaire observé: 40 kDa
• Numéro d’acquisition GenBank: BC051841
• Symbole du gène: TMEM25
• Identification du gène (NCBI): 84866
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TMEM25 is a novel member of the immunoglobulin superfamily. BC042896 and AY358919 cDNAs are derived from human TMEM25 gene. TMEM25 isoform 1 (BC042896), consisting of exons 1-9, encodes a 366-aa transmembrane protein. TMEM25 isoform 2 (AY358919), consisting of exons 1-4 and 6-9, encodes a 322-aa secreted protein (PMID:15254712). Human TMEM25 gene are found to encode transmembrane-type as well as secreted-type proteins due to alternative splicing of exon-skipping type. TMEM25 mRNA is expressed in brain, including cerebellar cortex and hippocampus, as well as in neuroblastoma, brain tumors, and gastric cancer. TMEM25 is a target of pharmacogenomics in the field of oncology and regenerative medicine. TMEM25 mRNAs may be useful members of a panel of favorable prognostic and predictive markers for breast cancer( PMID:19776672).

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