Anticorps Polyclonal de lapin anti-TMEM258

TMEM258 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31525-1-PBS

Synonymes

C11orf10

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Galerie de données de validation

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  WB analysis using 31525-1-AP (same clone as 31525-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31525-1-AP (TMEM258 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31525-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse small intestine using 31525-1-AP (same clone as 31525-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue slide using 31525-1-AP (TMEM258 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31525-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 31525-1-AP (same clone as 31525-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 31525-1-AP (TMEM258 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31525-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 31525-1-AP (same clone as 31525-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 31525-1-AP (TMEM258 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31525-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31525-1-PBS cible TMEM258 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TMEM258 Protéine recombinante Ag35142
• Nom complet: chromosome 11 open reading frame 10
• Poids moléculaire observé: 10 and 16 kDa
• Numéro d’acquisition GenBank: BC015968
• Symbole du gène: C11orf10
• Identification du gène (NCBI): 746
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TMEM258, or transmembrane protein 258, is a component of the oligosaccharyltransferase (OST) complex. Research has shown that TMEM258 is involved in controlling ER stress and intestinal inflammation. In particular, it has been identified as a central regulator of intestinal homeostasis. The loss of TMEM258 leads to unresolved ER stress, which can result in apoptosis (PMID: 27974209). The calculated MW is 9 kDa, The observed MW is multiple bands, which may be caused by Glycosylation modification.

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