Anticorps Polyclonal de lapin anti-TMEM33

TMEM33 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30639-1-PBS

Synonymes

Transmembrane protein 33, SHINC-3, SHINC3, Protein DB83, DB83

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Galerie de données de validation

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  WB analysis using 30639-1-AP (same clone as 30639-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30639-1-AP (TMEM33 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30639-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30639-1-PBS cible TMEM33 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TMEM33 Protéine recombinante Ag32368
• Nom complet: transmembrane protein 33
• Masse moléculaire calculée: 28 kDa
• Poids moléculaire observé: 27-30 kDa
• Numéro d’acquisition GenBank: BC000948
• Symbole du gène: TMEM33
• Identification du gène (NCBI): 55161
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TMEM33 (transmembrane protein 33), also known as DB83. It is expected to be located in endoplasmic reticulum membrane and nucleus envelope. The protein is widely expressed in prostate cancer and several cancer cell lines (at protein level). And expressed at higher levels in endocrine-resistant breast cancer cells as compared to endocrine-sensitive breast cancer cells. It is also expressed at higher levels in early recurrence breast cancer tissues as compared to non-recurrent breast tumors. The calculated molecular weight of TMEM33 is 28 kDa. It is suggest that TMEM33 has a potency to suppress the membrane-shaping activity of reticulons, thereby regulating the tubular structure of ER (PMID: 25612671).

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