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Anticorps Recombinant de lapin anti-TMEM41B

TMEM41B Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242017C11

N° de cat : 84510-4-PBS

Synonymes

Transmembrane protein 41B, KIAA0033, 242017C11

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using TMEM41B Recombinant antibody (84510-4-RR)

    WB analysis using 84510-4-RR (same clone as 84510-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84510-4-RR (TMEM41B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84510-4-PBS in a different storage buffer formulation.

Informations sur le produit

84510-4-PBS cible TMEM41B dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène TMEM41B Protéine recombinante Ag30810
Nom complet transmembrane protein 41B
Masse moléculaire calculée32 kDa
Poids moléculaire observé25-28 kDa
Numéro d’acquisition GenBankBC035034
Symbole du gène TMEM41B
Identification du gène (NCBI) 440026
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Transmembrane protein 41B (TMEM41B), also known as Stasimon, is a major target of survival motor neuron (SMN)-dependent U12 splicing and has been identified as a protein required for motor circuit function (PMID: 23063131). TMEM41B localizes to the endoplasmic reticulum. It is involved in autophagosome biogenesis and lipid mobilization (PMID: 30126924). TMEM41B has been shown to be essential for mouse embryonic development (PMID: 30352685). Additionally, genome-scale CRISPR knockout screens reveal that TMEM41B is required for infection of flavivirus and coronavirus, including SARS-CoV-2 (PMID: 33052348; 33052332). Alternative splicing results in three transcript variants encoding distinct isoforms.

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