Anticorps Recombinant de lapin anti-TMEM59

TMEM59 Recombinant Antibody for IF/ICC, FC (Intra), ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, FC (Intra), ELISA

Conjugaison

Non conjugué

CloneNo.

240457A1

N° de cat : 83656-3-PBS

Synonymes

UNQ169/PRO195, Liver membrane-bound protein, HSPC001, C1orf8, 240457A1

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Galerie de données de validation

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  IF Staining of HepG2 using 83656-3-RR (same clone as 83656-3-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using TMEM59 antibody (83656-3-RR, Clone: 240457A1 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83656-3-PBS in a different storage buffer formulation.

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  FC experiment of HepG2 using 83656-3-RR (same clone as 83656-3-PBS)

  1x10^6 HepG2 cells were intracellularly stained with 0.25 ug TMEM59 Recombinant antibody (83656-3-RR, Clone:240457A1) and APC-Conjugated Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 83656-3-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83656-3-RR

  Biolayer interferometry (BLl) kinetic assays of 83656-3-RR against Human TMEM59 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

83656-3-PBS cible TMEM59 dans les applications de IF/ICC, FC (Intra), ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TMEM59 Protéine recombinante Ag1968
• Nom complet: transmembrane protein 59
• Masse moléculaire calculée: 36 kDa
• Numéro d’acquisition GenBank: BC016374
• Symbole du gène: TMEM59
• Identification du gène (NCBI): 9528
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TMEM59 is a regulator of autophagy in response to bacterial infection. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing of TMEM59 results in multiple transcript variants.

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