Anticorps Monoclonal anti-TMEM70

• Phare
• Validé par KD/KO

TMEM70 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2C11C3

N° de cat : 60195-1-PBS

Synonymes

TMEM70, transmembrane protein 70

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Galerie de données de validation

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  WB analysis of A2780 using 60195-1-Ig (same clone as 60195-1-PBS)

  A2780 cells were subjected to SDS PAGE followed by western blot with 60195-1-Ig (TMEM70 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 60195-1-Ig (same clone as 60195-1-PBS)

  WB result of TMEM70 antibody (60195-1-Ig; 1:1500; incubated at room temperature for 1.5 hours) with sh-Control and sh-TMEM70 transfected HeLa cells. This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 60195-1-Ig (same clone as 60195-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver using 60195-1-Ig(TMEM70 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 60195-1-Ig (same clone as 60195-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver using 60195-1-Ig(TMEM70 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas using 60195-1-Ig (same clone as 60195-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas using 60195-1-Ig(TMEM70 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas using 60195-1-Ig (same clone as 60195-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas using 60195-1-Ig(TMEM70 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

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Informations sur le produit

60195-1-PBS cible TMEM70 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: TMEM70 Protéine recombinante Ag16947
• Nom complet: transmembrane protein 70
• Masse moléculaire calculée: 260 aa, 29 kDa
• Poids moléculaire observé: 18 kDa
• Numéro d’acquisition GenBank: BC002748
• Symbole du gène: TMEM70
• Identification du gène (NCBI): 54968
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TMEM70 belongs to the TMEM70 family. It is involved in biogenesis of mitochondrial ATP synthase. Defects in TMEM70 are a cause of mitochondrial encephalocardiomyopathy neonatal due to ATP synthase deficiency (MT-ATPSD). A publication (PMID:21147908) identified TMEM70 gene defect as a pan-ethnic disorder and further redefined it as the most common cause of nuclear-origin ATP synthase deficiency.

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