Anticorps Polyclonal de lapin anti-TMPRSS11D

TMPRSS11D Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24634-1-PBS

Synonymes

HAT, MAT, RAT

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Galerie de données de validation

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  WB analysis using 24634-1-AP (same clone as 24634-1-PBS)

  A-253 cells were subjected to SDS PAGE followed by western blot with 24634-1-AP (TMPRSS11D antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24634-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24634-1-PBS cible TMPRSS11D dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TMPRSS11D Protéine recombinante Ag17841
• Nom complet: transmembrane protease, serine 11D
• Masse moléculaire calculée: 418 aa, 46 kDa
• Poids moléculaire observé: 46 kDa
• Numéro d’acquisition GenBank: BC125195
• Symbole du gène: TMPRSS11D
• Identification du gène (NCBI): 9407
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TMPRSS11D, also known as human airway trypsin-like protease (HAT), is a type II transmembrane serine protease that plays a crucial role in various biological processes, including viral infections and cancer progression. This protease is expressed in the epithelial cells of the respiratory tract and has been implicated in the activation of several viruses, such as SARS-CoV-2. In addition to its role in viral infections, TMPRSS11D has also been involved in cancer progression. High expression levels of TMPRSS11D have been associated with poor overall survival in non-small cell lung cancer. This suggests that TMPRSS11D may contribute to tumor growth and metastasis, making it a potential biomarker and therapeutic target in oncology. (PMID: 28086212, PMID: 40348740)

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