Anticorps Recombinant de lapin anti-TNC/Tenascin-C

TNC/Tenascin-C Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242866C6

N° de cat : 85821-1-PBS

Synonymes

Hexabrachion, Hxb, Tenascin, Tenascin-C, TN

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Galerie de données de validation

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  WB analysis of mouse colon using 85821-1-RR (same clone as 85821-1-PBS)

  mouse colon tissue were subjected to SDS PAGE followed by western blot with 85821-1-RR (Tnc antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85821-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse thymus using 85821-1-RR (same clone as 85821-1-PBS)

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 85821-1-RR (Tnc antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85821-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85821-1-PBS cible TNC/Tenascin-C dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TNC/Tenascin-C Protéine recombinante Eg2849
• Nom complet: tenascin C
• Masse moléculaire calculée: 232 kDa
• Poids moléculaire observé: 210-230 kDa
• Numéro d’acquisition GenBank: N/A
• Symbole du gène: Tnc
• Identification du gène (NCBI): 21923
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Tenascin-C (TNC) is a large hexameric extracellular matrix glycoprotein of the tenascin family (PMID: 21818551). It is a multimodular protein containing multiple epidermal growth factor (EGF)-like repeats and fibronectin type III (FN III) domains (PMID: 1719530). Tenascin-C is highly expressed during embryonic development, particularly in the developing central nervous system, around motile cells and at epithelial-mesenchymal interaction sites (PMID: 25738825). In adult tissues, the expression and the distribution of TNC are typically limited under normal physiological conditions. It is upregulated during injury, inflammation, regeneration, and cancer (PMID: 7694605; 25120494). Tenascin-C is a diverse protein that can produce different functions including regulating cell adhesion, migration and proliferation.

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