Anticorps Polyclonal de lapin anti-TNFAIP8

• Phare
• Validé par KD/KO

TNFAIP8 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 15790-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 15790-1-AP (same clone as 15790-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 15790-1-AP (TNFAIP8 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15790-1-PBS in a different storage buffer formulation.

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  WB analysis of A549 using 15790-1-AP (same clone as 15790-1-PBS)

  A549 cells were subjected to SDS PAGE followed by western blot with 15790-1-AP (TNFAIP8 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15790-1-PBS in a different storage buffer formulation.

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  WB analysis of PC-13 using 15790-1-AP (same clone as 15790-1-PBS)

  PC-13 cells were subjected to SDS PAGE followed by western blot with 15790-1-AP (TNFAIP8 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15790-1-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 15790-1-AP (same clone as 15790-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis slide using 15790-1-AP (TNFAIP8 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 15790-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 15790-1-AP (same clone as 15790-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer slide using 15790-1-AP (TNFAIP8 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 15790-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 15790-1-AP (same clone as 15790-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis slide using 15790-1-AP (TNFAIP8 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 15790-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 15790-1-AP (same clone as 15790-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer slide using 15790-1-AP (TNFAIP8 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 15790-1-PBS in a different storage buffer formulation.

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Informations sur le produit

15790-1-PBS cible TNFAIP8 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TNFAIP8 Protéine recombinante Ag8491
• Nom complet: tumor necrosis factor, alpha-induced protein 8
• Masse moléculaire calculée: 198 aa, 23 kDa
• Poids moléculaire observé: 19-23 kDa
• Numéro d’acquisition GenBank: BC007014
• Symbole du gène: TNFAIP8
• Identification du gène (NCBI): 25816
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TNFAIP8 (tumor necrosis factor, alpha-induced protein 8), also called SCC-S2/GG2-1/NDED, is associated with enhanced cell survival and inhibition of apoptosis. The induction of TNFAIP8 by TNF depends on the activation of NFκB. TNFAIP8 suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. TNFAIP8 is expressed in adult spleen, lymph node, thymus, thyroid, bone marrow, and placenta, and in fetal liver, lung, and kidney at high levels, also expressed in various tumor tissues and all cancer cell lines tested. There are four major isoforms of TNFAIP8.

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