Anticorps Polyclonal de lapin anti-TNFRSF13B/CD267

TNFRSF13B/CD267 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 21520-1-AP

Synonymes

CD267, TNFRSF13B, TACI, CVID

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Galerie de données de validation

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  WB analysis using 21520-1-AP

  IM-9 cells were subjected to SDS PAGE followed by western blot with 21520-1-AP (TNFRSF13B/CD267 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

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  WB analysis of K-562 using 21520-1-AP

  K-562 cells were subjected to SDS PAGE followed by western blot with 21520-1-AP (TNFRSF13B antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: IM-9 cells, cellules K-562

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

21520-1-AP cible TNFRSF13B/CD267 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TNFRSF13B/CD267 Protéine recombinante Ag16097
• Nom complet: tumor necrosis factor receptor superfamily, member 13B
• Masse moléculaire calculée: 293 aa, 32 kDa
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: BC109392
• Symbole du gène: TNFRSF13B/CD267
• Identification du gène (NCBI): 23495
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), also known as CD267 or TACI, is a transmembrane protein of the TNF receptor superfamily found predominantly on B cells (PMID: 10920230). TACI is also expressed on activated T cells, myeloma cells, and expressed by monocytes intracellularly at a low level (PMID: 11429548; 16825497). TNFRSF13B is a receptor for TNFSF13/APRIL/CD256 and TNFSF13B/BAFF/CD257 and mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-κB and AP-1 (PMID: 10956646; 10973284; 9311921). It is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.

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