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Anticorps Recombinant de lapin anti-TNFRSF13B/CD267

TNFRSF13B/CD267 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241317C9

N° de cat : 84266-3-PBS

Synonymes

CD267, TNFRSF13B, 241317C9, CVID, TACI

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using TNFRSF13B/CD267 Recombinant antibody (84266-3-RR)

    WB analysis using 84266-3-RR (same clone as 84266-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84266-3-RR (TNFRSF13B/CD267 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84266-3-PBS in a different storage buffer formulation.

Informations sur le produit

84266-3-PBS cible TNFRSF13B/CD267 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Protéine recombinante
Nom complet tumor necrosis factor receptor superfamily, member 13B
Masse moléculaire calculée 293 aa, 32 kDa
Poids moléculaire observé32 kDa
Numéro d’acquisition GenBankBC109392
Symbole du gène TNFRSF13B/CD267
Identification du gène (NCBI) 23495
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), also known as CD267 or TACI, is a transmembrane protein of the TNF receptor superfamily found predominantly on B cells (PMID: 10920230). TACI is also expressed on activated T cells, myeloma cells, and expressed by monocytes intracellularly at a low level (PMID: 11429548; 16825497). TNFRSF13B is a receptor for TNFSF13/APRIL/CD256 and TNFSF13B/BAFF/CD257 and mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-κB and AP-1 (PMID: 10956646; 10973284; 9311921). It is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.

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