Anticorps Recombinant de lapin anti-TNFRSF13B/CD267

TNFRSF13B/CD267 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241317D8

N° de cat : 98100-1-RR

Synonymes

CD267, TNFRSF13B, 241317D8, CVID, TACI

---

Galerie de données de validation

• 

  FC experiment of human PBMCs using 98100-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human TNFRSF13B/CD267 Rabbit RecAb (98100-1-RR, Clone:241317D8) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD19 (4G7) Mouse IgG2a Recombinant Antibody (CL647-65562, Clone: 4G7). Cells were not fixed. Lymphocytes were gated.

• 

  Affinity and Kinetic Characterization of 98100-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98100-1-RR against Human TNFRSF13B/CD267 were performed. The affinity constant is 4.18 nM.

---

Applications testées

• Résultats positifs en cytométrie: CMSP humaines,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98100-1-RR cible TNFRSF13B/CD267 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: tumor necrosis factor receptor superfamily, member 13B
• Masse moléculaire calculée: 293 aa, 32 kDa
• Numéro d’acquisition GenBank: BC109392
• Symbole du gène: TNFRSF13B/CD267
• Identification du gène (NCBI): 23495
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), also known as CD267 or TACI, is a transmembrane protein of the TNF receptor superfamily found predominantly on B cells (PMID: 10920230). TACI is also expressed on activated T cells, myeloma cells, and expressed by monocytes intracellularly at a low level (PMID: 11429548; 16825497). TNFRSF13B is a receptor for TNFSF13/APRIL/CD256 and TNFSF13B/BAFF/CD257 and mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-κB and AP-1 (PMID: 10956646; 10973284; 9311921). It is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.

{{ptg:RelatedPrimaryAntibodies}}