Anticorps Monoclonal anti-CD268/BAFF-R

CD268/BAFF-R Monoclonal Antibody for Cytometric bead array, Indirect ELISA

Hôte / Isotype

Mouse / IgM

Réactivité testée

Humain

Applications

Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2D5B1

N° de cat : 60763-2-PBS

Synonymes

TNFRSF13C, B-cell-activating factor receptor, BAFF-R, BAFFR, BAFF receptor

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Galerie de données de validation

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  Cytometric bead array standard curve of MP51091-1

  Cytometric bead array standard curve of MP51091-1, TNFRSF13C Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60763-1-PBS. Detection antibody: 60763-2-PBS. Standard:Ag18512. Range: 0.098-100 ng/mL.

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  Cytometric bead array standard curve of MP51091-3

  Cytometric bead array standard curve of MP51091-3, TNFRSF13C Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60763-2-PBS. Detection antibody: 60763-4-PBS. Standard:Ag18512. Range: 0.391-100 ng/mL.

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  Cytometric bead array standard curve of MP51091-4

  Cytometric bead array standard curve of MP51091-4, TNFRSF13C Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60763-2-PBS. Detection antibody: 60763-3-PBS. Standard:Ag18512. Range: 0.781-100 ng/mL.

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Informations sur le produit

60763-2-PBS cible CD268/BAFF-R dans les applications de Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgM
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CD268/BAFF-R Protéine recombinante Ag18512
• Nom complet: tumor necrosis factor receptor superfamily, member 13C
• Masse moléculaire calculée: 184 aa, 19 kDa
• Numéro d’acquisition GenBank: BC105123
• Symbole du gène: TNFRSF13C
• Identification du gène (NCBI): 115650
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Précipitation de l'acide caprylique/du sulfate d'ammonium
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453).

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