Anticorps Polyclonal de lapin anti-TNFRSF9/CD137

TNFRSF9/CD137 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32133-1-PBS

Synonymes

T-cell antigen 4-1BB, Ly63, Ila, CD137, 4-1BB ligand receptor

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Galerie de données de validation

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  WB analysis using 32133-1-AP (same clone as 32133-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32133-1-AP (4-1BB/TNFRSF9 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32133-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32133-1-PBS cible TNFRSF9/CD137 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: tumor necrosis factor receptor superfamily, member 9
• Masse moléculaire calculée: 28 kDa
• Poids moléculaire observé: 28-30 kDa, 40-45 kDa
• Numéro d’acquisition GenBank: NM_001077509.1
• Symbole du gène: Tnfrsf9
• Identification du gène (NCBI): 21942
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD137, also known as TNFRSF9 or 4-1BB, is an inducible T cell surface receptor that belongs to the tumor necrosis factor receptor superfamily. CD137 is a transmembrane protein expressed on the surface of activated T-cells. In addition, activation-dependent expression of CD137 has also been found in B lymphocytes, monocytes, and diverse nonlymphoid cell types. CD137 provides a co-stimulatory signal that enhances the survival, and differentiation of cells, and has a crucial role in the development of CD8 cytotoxic T cells and anti-tumor immunity. (PMID: 9826581; 23696891)

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