Anticorps Recombinant de lapin anti-TNFRSF9/CD137

TNFRSF9/CD137 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

241647E11

N° de cat : CL647-98182

Synonymes

241647E11, 4-1BB, 4-1BB ligand receptor, CD137, Ila

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Galerie de données de validation

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  FC experiment of mouse splenocytes using CL647-98182

  1x10^6 untreated or Con A treated mouse splenocytes were surface stained with FITC Plus Anti-Mouse CD25/IL-2RA and 0.25 ug CoraLite® Plus 647 Anti-Mouse TNFRSF9/CD137 Rabbit RecAb (CL647-98182, Clone: 241647E11). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: Con A treated mouse splenocytes,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL647-98182 cible TNFRSF9/CD137 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: tumor necrosis factor receptor superfamily, member 9
• Masse moléculaire calculée: 28 kDa
• Numéro d’acquisition GenBank: NM_001077509.1
• Symbole du gène: Tnfrsf9
• Identification du gène (NCBI): 21942
• Conjugaison: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD137, also known as TNFRSF9 or 4-1BB, is an inducible T cell surface receptor that belongs to the tumor necrosis factor receptor superfamily. CD137 is a transmembrane protein expressed on the surface of activated T-cells. In addition, activation-dependent expression of CD137 has also been found in B lymphocytes, monocytes, and diverse nonlymphoid cell types. CD137 provides a co-stimulatory signal that enhances the survival, and differentiation of cells, and has a crucial role in the development of CD8 cytotoxic T cells and anti-tumor immunity. (PMID: 9826581; 23696891)

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