Anticorps Recombinant de lapin anti-TNFRSF9/CD137

TNFRSF9/CD137 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

FITC Plus Fluorescent Dye

CloneNo.

241344F3

N° de cat : FITC-98112

Synonymes

TNFRSF9, 241344F3, 4 1BB, 4 1BB ligand receptor, 4-1BB ligand receptor

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Galerie de données de validation

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  FC experiment of human PBMCs using FITC-98112

  1x10^6 untreated or Con-A treated human PBMCs were surface stained with APC Anti-Human CD8 (UCHT4) Mouse IgG2a Recombinant Antibody (APC-65559, Clone: UCHT4) and 5 ul FITC Plus Anti-Human TNFRSF9/CD137 Rabbit RecAb (FITC-98112, Clone: 241344F3). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: Con-A treated human PBMCs

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

FITC-98112 cible TNFRSF9/CD137 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: tumor necrosis factor receptor superfamily, member 9
• Masse moléculaire calculée: 28 kDa
• Numéro d’acquisition GenBank: BC006196
• Symbole du gène: TNFRSF9/CD137
• Identification du gène (NCBI): 3604
• Conjugaison: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD137, also known as TNFRSF9 or 4-1BB, is an inducible T cell surface receptor that belongs to the tumor necrosis factor receptor superfamily. CD137 is a transmembrane protein expressed on the surface of activated T-cells. In addition, activation-dependent expression of CD137 has also been found in B lymphocytes, monocytes, and diverse nonlymphoid cell types. CD137 provides a co-stimulatory signal that enhances the survival, and differentiation of cells, and has a crucial role in the development of CD8 cytotoxic T cells and anti-tumor immunity. (PMID: 9826581; 23696891)

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