Anticorps Polyclonal de lapin anti-TOM1L2

TOM1L2 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32179-1-PBS

Synonymes

Target Of Myb1 Like 2 Membrane Trafficking Protein, Target of Myb-like protein 2, TOM1-like protein 2

---

Galerie de données de validation

• 

  WB analysis using 32179-1-AP (same clone as 32179-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32179-1-AP (TOM1L2 antibody) at dilution of 1:15000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32179-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse brain using 32179-1-AP (same clone as 32179-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 32179-1-AP (TOM1L2 antibody) at dilution of 1:15000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32179-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 32179-1-AP (same clone as 32179-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32179-1-AP (TOM1L2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32179-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse cerebellum using 32179-1-AP (same clone as 32179-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 32179-1-AP (TOM1L2 antibody) at dilution of 1:600 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32179-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse cerebellum using 32179-1-AP (same clone as 32179-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 32179-1-AP (TOM1L2 antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32179-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HeLa using 32179-1-AP (same clone as 32179-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using TOM1L2 antibody (32179-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 32179-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

32179-1-PBS cible TOM1L2 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TOM1L2 Protéine recombinante Ag37612
• Nom complet: target of myb1-like 2 (chicken)
• Masse moléculaire calculée: 56 kDa，507aa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: NM_001082968.1
• Symbole du gène: TOM1L2
• Identification du gène (NCBI): 146691
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Target of Myb-like protein 2 (TOM1L2) acts as a MYO6/Myosin VI adapter protein that targets myosin VI to endocytic structures (PMID: 23023224). It may play a role in recruiting clathrin to endosomes and regulating growth factor-induced mitogenic signaling (PMID: 16412388; 16479011). TOM1L2 also regulates membrane trafficking that is linked to immunity and cell proliferation (PMID: 20604899).

{{ptg:RelatedPrimaryAntibodies}}