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Anticorps Recombinant de lapin anti-TOM70

TOM70 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251874H2

N° de cat : 86840-3-PBS

Synonymes

TOMM70A, KIAA0719, TOMM, TOMM70, Translocase of outer mitochondrial membrane protein 70

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using TOM70 Recombinant monoclonal antibody (86840-3-RR)

    WB analysis using 86840-3-RR (same clone as 86840-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86840-3-RR (TOM70 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86840-3-PBS in a different storage buffer formulation.

Informations sur le produit

86840-3-PBS cible TOM70 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène TOM70 Protéine recombinante Ag6027
Nom complet translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
Masse moléculaire calculée 67 kDa
Poids moléculaire observé 70 kDa
Numéro d’acquisition GenBankBC052994
Symbole du gène TOM70
Identification du gène (NCBI) 9868
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TOMM70A (or TOM70) is a mitochondrial import receptor responsible for the import of cytosol synthesized precursor proteins into the mitochondria. Tom70 is a member of the tetratricopeptide repeat (TPR) co-chaperone family and contains a conserved TPR clamp domain for interaction with Hsc70 and Hsp90. Recently overexpression of TOM70 has been linked to chemoresistance to drugs in breast cancer cell lines. It is also believed that Tom70 is significantly associated with breast cancer relapse and may predict the recurrence of ovarian cancer.

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