Anticorps Recombinant de lapin anti-TOR1B

TOR1B Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241574A7

N° de cat : 84267-3-PBS

Synonymes

241574A7, DQ1, Torsin 1B, Torsin family 1 member B

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Galerie de données de validation

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  WB analysis using 84267-3-RR (same clone as 84267-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84267-3-RR (TOR1B antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84267-3-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP01175-1

  Cytometric bead array standard curve of MP01175-1, TOR1B Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84267-1-PBS. Detection antibody: 84267-3-PBS. Standard: Ag16641. Range: 0.313-40 ng/mL.

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  Cytometric bead array standard curve of MP01175-2

  Cytometric bead array standard curve of MP01175-2, TOR1B Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84267-2-PBS. Detection antibody: 84267-3-PBS. Standard: Ag16641. Range: 0.313-40 ng/mL.

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  Affinity and Kinetic Characterization of 84267-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84267-3-RR against Human TOR1B were performed. The affinity constant is 14.5 nM.

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Informations sur le produit

84267-3-PBS cible TOR1B dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TOR1B Protéine recombinante Ag16641
• Nom complet: torsin family 1, member B (torsin B)
• Masse moléculaire calculée: 336 aa, 38 kDa
• Poids moléculaire observé: 35 kDa
• Numéro d’acquisition GenBank: BC015578
• Symbole du gène: TOR1B
• Identification du gène (NCBI): 27348
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Torsin A is 1 of 4 predicted mammalian torsin ATPases associated with assorted cellular activities (AAA+) proteins (PMID: 20015956). TOR1B (torsin family 1 member B), also called TorsinB (TorB), is similar to TorsinA at the sequence level. TorsinA and TorsinB are both ubiquitously expressed in all cell types though TorsinA is more highly expressed in neurons. TorsinA and TorsinB may be somewhat functionally redundant, with TorsinA being more important in neuronal cells and TorsinB being more important in other tissues (PMID: 24275647). TOR1B serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins,and plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity (PMID: 24275647; 23569223).

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