Anticorps Polyclonal de lapin anti-TOX2

TOX2 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30474-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 30474-1-AP (same clone as 30474-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30474-1-AP (TOX2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30474-1-PBS in a different storage buffer formulation.

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  IF Staining of A431 using 30474-1-AP (same clone as 30474-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed A431 cells using TOX2 antibody (30474-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 30474-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30474-1-PBS cible TOX2 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TOX2 Protéine recombinante Ag31226
• Nom complet: TOX high mobility group box family member 2
• Masse moléculaire calculée: 488 aa, 52 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC007636
• Symbole du gène: TOX2
• Identification du gène (NCBI): 84969
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TOX2 is a transcription factor belonging to the TOX (thymocyte selection-associated HMG box) family that shares a highly conserved high mobility group DNA-binding domain with the other TOX members. A previous study showed that TOX2 is preferentially expressed in human NK cells among various leukocyte populations and is required for in vitro and in vivo human NK cell differentiation from UCB-derived CD341 hematopoietic stem cells (HSCs) (PMID: 25352127).

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