Anticorps Monoclonal anti-TOX2

TOX2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, Lapin, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2G12A7

N° de cat : 68590-1-PBS

Synonymes

2G12A7, C20orf100, GCX1, GCX-1

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Galerie de données de validation

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  WB analysis using 68590-1-Ig (same clone as 68590-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68590-1-Ig (TOX2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 68590-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68590-1-Ig (same clone as 68590-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68590-1-Ig (TOX2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 68590-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68590-1-PBS cible TOX2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, rat, souris

• Réactivité: Humain, Lapin, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: TOX2 Protéine recombinante Ag31563
• Nom complet: TOX high mobility group box family member 2
• Masse moléculaire calculée: 52KD
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: NM_001098797
• Symbole du gène: TOX2
• Identification du gène (NCBI): 84969
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TOX2 is a transcription factor belonging to the TOX (thymocyte selection-associated HMG box) family that shares a highly conserved high mobility group DNA-binding domain with the other TOX members. A previous study showed that TOX2 is preferentially expressed in human NK cells among various leukocyte populations and is required for in vitro and in vivo human NK cell differentiation from UCB-derived CD341 hematopoietic stem cells (HSCs) (PMID: 25352127).

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