Anticorps Monoclonal anti-p63

p63 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

4D6G12

N° de cat : 60332-2-PBS

Synonymes

TP63, tumor protein p63, Tumor protein 63, Transformation-related protein 63, TP 63

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Galerie de données de validation

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  WB analysis of HaCaT using 60332-2-Ig (same clone as 60332-2-PBS)

  HaCaT cells were subjected to SDS PAGE followed by western blot with 60332-2-Ig (TP63 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

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  WB analysis of A431 using 60332-2-Ig (same clone as 60332-2-PBS)

  A431 cells were subjected to SDS PAGE followed by western blot with 60332-2-Ig (TP63 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

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  WB analysis of U-937 using 60332-2-Ig (same clone as 60332-2-PBS)

  U-937 cells were subjected to SDS PAGE followed by western blot with 60332-2-Ig (TP63 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

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  IHC staining of rat skin using 60332-2-Ig (same clone as 60332-2-PBS)

  Immunohistochemical analysis of paraffin-embedded rat skin tissue slide using 60332-2-Ig (TP63 antibody) at dilution of 1:4000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 60332-2-Ig (same clone as 60332-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60332-2-Ig (TP63 antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

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  IHC staining of mouse skin using 60332-2-Ig (same clone as 60332-2-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 60332-2-Ig (TP63 antibody) at dilution of 1:4000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 60332-2-Ig (same clone as 60332-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 60332-2-Ig (TP63 antibody) at dilution of 1:4000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 60332-2-Ig (same clone as 60332-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60332-2-Ig (TP63 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 60332-2-Ig (same clone as 60332-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60332-2-Ig (TP63 antibody) at dilution of 1:4000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60332-2-PBS in a different storage buffer formulation.

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Informations sur le produit

60332-2-PBS cible p63 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: p63 Protéine recombinante Ag2791
• Nom complet: tumor protein p63
• Masse moléculaire calculée: 680 aa, 77 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC039815
• Symbole du gène: TP63
• Identification du gène (NCBI): 8626
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40), 50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.

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