Anticorps Polyclonal de lapin anti-TRAF6

• Phare
• Validé par KD/KO

TRAF6 Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain et plus (2)

Applications

WB, IF, ELISA

Conjugaison

Non conjugué

Publications(18)

N° de cat : 12809-1-AP

Synonymes

RING finger protein 85, RNF85, TRAF6

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Galerie de données de validation

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Applications publiées

• KD/KO: See 1 publications below
• WB: See 18 publications below
• IF: See 2 publications below

Informations sur le produit

12809-1-AP cible TRAF6 dans les applications de WB, IF, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TRAF6 Protéine recombinante Ag3555
• Nom complet: TNF receptor-associated factor 6
• Masse moléculaire calculée: 522 aa, 60 kDa
• Numéro d’acquisition GenBank: BC031052
• Symbole du gène: TRAF6
• Identification du gène (NCBI): 7189
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF6 is recognized as a signal transducer, which activates the NF-κB pathway in response to pro-inflammatory cytokines. TRAF6 has E3 ligase activity and is responsible for inducing Lys-63 (K63)-linked poly-ubiquitination chains, functioning together with E2 Ubc13/Uev1A complex to mediate IKK activation TRAF6 plays a crucial role in the regulation of the innate and adaptive immune responses.

Publications

Species	Application	Title
human	WB, IF	Nat Immunol; Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity.; Authors - Jing Geng
human	WB	Autophagy; TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.; Authors - Tianyu Han ; KD Validated
rat	WB	Front Immunol; Emodin Alleviates Sodium Taurocholate-Induced Pancreatic Acinar Cell Injury via MicroRNA-30a-5p-Mediated Inhibition of High-Temperature Requirement A/Transforming Growth Factor Beta 1 Inflammatory Signaling.; Authors - Hong Xiang
human	WB	Mol Cancer Res; TAGLN Is Downregulated by TRAF6-Mediated Proteasomal Degradation in Prostate Cancer Cells.; Authors - Fuping Wen
human	WB	Front Pharmacol; Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.; Authors - Hong Yao
rat	WB	Eur J Immunol; Gx-50 reduces β-amyloid-induced TNF-α, IL-1β, NO and PGE2 expression and inhibits NF- κB signaling in a mouse model of Alzheimer's disease.; Authors - Shi Shi

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