Anticorps Polyclonal de lapin anti-TRAIL

TRAIL Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, FC, ELISA

Conjugaison

Non conjugué

Publications(5)

N° de cat : 17235-1-AP

Synonymes

Apo 2 ligand, Apo 2L, APO2L, CD253, Protein TRAIL, TL2, TNFSF10, TRAIL

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Galerie de données de validation

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Applications publiées

• WB: See 4 publications below
• FC: See 1 publications below

Informations sur le produit

17235-1-AP cible TRAIL dans les applications de WB, FC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TRAIL Protéine recombinante Ag11078
• Nom complet: tumor necrosis factor (ligand) superfamily, member 10
• Masse moléculaire calculée: 281 aa, 33 kDa
• Numéro d’acquisition GenBank: BC032722
• Symbole du gène: TRAIL
• Identification du gène (NCBI): 8743
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

TRAIL is a 30 kD protein known as TNF-related apoptosis inducing ligand, CD253, TNFSF10, or Apo-2L. It is expressed as two kinds of forms: cell surface protein (30 kD) and soluble ligand (19-20 kD) produced by megakaryocytes and platelets, monocytes, neutrophils, NK cells and activated T cells. This antigen is also expressed on tumor cells and transformed cell lines. TRAIL has been reported to induce apoptosis in tumor and transformed cell lines by a caspase-dependent process.

Publications

Species	Application	Title
human	WB	Int J Cancer; Targeted knockdown of Bcl2 in tumor cells using a synthetic TRAIL 3'-UTR microRNA.; Authors - Jianjun Zhang
	WB	J Immunol; The calcineurin B subunit (CnB) is a new ligand of integrin αM that mediates CnB-induced Apo2L/TRAIL expression in macrophages.; Authors - Liu Lixin L
human	WB	Cell Death Dis; Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells: an in vitro and in vivo study.; Authors - H-Y Li
human	FC	J Immunol; Both HIV-Infected and Uninfected Cells Express TRAILshort, Which Confers TRAIL Resistance upon Bystander Cells within the Microenvironment.; Authors - Zilin Nie
human	WB	Biochem Biophys Res Commun; The calcineurin B subunit induces TNF-related apoptosis-inducing ligand (TRAIL) expression via CD11b-NF-κB pathway in RAW264.7 macrophages.; Authors - Su Zhenyi Z

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