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Anticorps Recombinant de lapin anti-TRAIP

TRAIP Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251370C8

N° de cat : 86808-1-PBS

Synonymes

TRIP, EC:2.3.2.27, RING finger protein 206, RNF206, TRAF interacting protein

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using TRAIP Recombinant monoclonal antibody (86808-1-RR)

    WB analysis using 86808-1-RR (same clone as 86808-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86808-1-RR (TRAIP antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86808-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86808-1-RR

    Affinity and Kinetic Characterization of 86808-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86808-1-RR against Human TRAIP were performed. The affinity constant is below 1 pM.

Informations sur le produit

86808-1-PBS cible TRAIP dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène TRAIP Protéine recombinante Ag0491
Nom complet TRAF interacting protein
Masse moléculaire calculée 53 kDa
Poids moléculaire observé 53 kDa
Numéro d’acquisition GenBankBC000310
Symbole du gène TRAIP
Identification du gène (NCBI) 10293
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

E3 ubiquitin-protein ligase TRAIP (TRAIP) is also named RING finger protein 206 (RNF206) and TRAF-interacting protein (TRIP). TRAIP, an E3 ligase containing a RING domain, has emerged as a significant contributor to maintaining genome integrity and TRAIP inhibits proliferation and migration of BLCA cells (PMID: 38123820). TRAIP helps replisomes overcome DNA interstrand crosslinks and DNA-protein crosslinks, whereas in mitosis it triggers disassembly of all replisomes that remain on chromatin (PMID: 33317933, PMID: 30842657).

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