Anticorps Polyclonal de lapin anti-TRANK1

TRANK1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 27583-1-AP

Synonymes

KIAA0342, LBA1, lupus brain antigen 1, Lupus brain antigen 1 homolog, TRANK1

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Galerie de données de validation

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  WB analysis using 27583-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 27583-1-AP (TRANK1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  IHC staining of human ovary cancer using 27583-1-AP

  Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 27583-1-AP (TRANK1 antibody) at dilution of 1:100 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Applications testées

• Résultats positifs en WB: cellules Raji,

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

27583-1-AP cible TRANK1 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TRANK1 Protéine recombinante Ag26206
• Nom complet: lupus brain antigen 1
• Masse moléculaire calculée: 336 kDa
• Poids moléculaire observé: ~330 kDa
• Numéro d’acquisition GenBank: NM_014831
• Symbole du gène: LBA1
• Identification du gène (NCBI): 9881
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Etratricopeptide repeat and ankyrin repeat containing 1 (TRANK1), has been confirmed as the susceptibility gene for BD (bipolar disorder). An integrated analysis of mRNA co-expression networks revealed that genes highly correlated with TRANK1 were significantly involved in the biological processes related to synaptic plasticity, dendritic spine, axon guidance and circadian rhythm. In addition, TRANK1 rs71947856 variant was associated with circadian regulation and Kleine-Levin syndrome, which is a rare disease characterized by severe episodic hypersomnia, with cognitive impairment and apathy or disinhibition.(PMID: 34014031)

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