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Anticorps Polyclonal de lapin anti-TREK1/KCNK2

TREK1/KCNK2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 26807-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using TREK1/KCNK2 Polyclonal antibody (26807-1-AP)

    WB analysis using 26807-1-AP (same clone as 26807-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 26807-1-AP (TREK1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26807-1-PBS in a different storage buffer formulation.

Informations sur le produit

26807-1-PBS cible TREK1/KCNK2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène TREK1/KCNK2 Protéine recombinante Ag25209
Nom complet potassium channel, subfamily K, member 2
Masse moléculaire calculée 411 aa, 46 kDa
Poids moléculaire observé40-50 kDa
Numéro d’acquisition GenBankBC101693
Symbole du gène TREK1
Identification du gène (NCBI) 3776
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The tandem of pore domains in a weak inward rectifying K+ channel (TWIK1, K2P1.1, or KCNK1) and TWIK-related K+channel 1 (TREK1, K2P 2.1, or KCNK2) are members of the two pore domain potassium (K2P) channel family, consisting of 15 channels that regulate the stabilization of resting membrane potential and cellular excitability by wielding background K+ leakage currents (PMID:12580339). TREK1/KCNK2 is sensitive to a wide range of physical and chemical cues. Its main role is to maintain the resting potential of the cell and whilst highly expressed in the nervous system, TREK1/KCNK2 is also expressed in the kidney, heart, lung and smooth muscle cells (PMID:31031627).

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